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Autoantibodies also have the possible to lead to interference in troponin immunometric assay strategies. Wrong-optimistic or Bogus-negative values may come up, determined by whether or not the autoantibody-analyte sophisticated partitions into the cost-free or maybe the bound analyte portion.
[71] Scientific studies have also proposed that the kidneys have some part in clearing troponin from circulation, Whilst there's no evidence of troponin in urine. This tends to complicate the analysis of a CKD individual who presents towards the emergency Section complaining of upper body discomfort using an elevated troponin.[seventy two]
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